Shaunodon on 15 September 2019
I haven't got around to the main Yakuza games yet, but as a general rule I'd say just to finish the story if you're already that far through.
Best thing about that, is you can make a clean finish and take a break from the series if need be. When you want to come back, you'll be starting from a new fresh point, rather than have to worry about remembering any ongoing subplots.
