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Wii Sports without question. It was synonymous with the Wii. It was why the console went viral.

Second to that, but first among dedicated gamers, is Halo. Halo made Xbox a thing. It was a massive success in that regard. I don't believe the history of Xbox would be nearly as good without Microsoft acquiring Halo. Halo was all over the place during that time and everyone was talking about. It was a really big deal.

I don't think any of the other games on that list had nearly as much impact.