Obviously Metroid Prime 4.
We won't see Final Fantasy VII Remake (the first installment that is, cuz remember - it's been confirmed to be episodic) until 2022 AT THE EARLIEST... Cuz once the PS5 lands, (just like the PS4 did in Versus XIII's development on PS3) Tetsuya Nomura, being the graphics perfectionist freakazoid that he is, will make the production team go through the game AGAIN on the PS5 hardware - just like he did with Versus XIII/FF15.
That's not a joke, and sure as metaphysical 100% certainty WILL happen. Graphic fidelity is EVERYTHING to that man, his reputation for being a graphics whore is infamous. I'm dead f***ing serious.