For me any char that doesn't have their sexuality mentioned are better than ones that have, unless of course the sexuality is a need on the plot then you can certainly have relationship values and dynamic as you choose and makes sense for that story.
So since I pay no attention to this unless they make a need to point out I would only know of Ellie and then the discussion about Nadine and Chloe being lesbian or bissexual.
Besides some WRPG where you can be transgender and have relationship with anyone you want and some japanese dating simulators.
duduspace11 "Well, since we are estimating costs, Pokemon Red/Blue did cost Nintendo about $50m to make back in 1996"
Mr Puggsly: "Hehe, I said good profit. You said big profit. Frankly, not losing money is what I meant by good. Don't get hung up on semantics"