Let me ask you a different question.
What if we made Lara Croft into a man? It would suck. Why? Coz that character was meant to be a strong female breaking barriers. It won't make any sense whatsoever if she were a man.
That's the same as what's going on with changing the gender or sexual orientation of established characters. It doesn't make sense with the story background and motivations of the character!
Are the new Ghostbusters supposed to be the same characters as the old ones? I'm almost sure that they're not.