Region-free --------> Success
Region-locked -----> Failure
Speaking of region-locking, it reminds me of all the support from small/medium sized developers from Japan that the Vita got. Maybe with the extra power, portability, lack of awkward gimmicks, standardized controls/display and (supposedly) easier coding, some of them will start to also develop on the NS.
Also, if the NS is region-free, it has to allow for some way to easily patch in fan-translations because I don't want to deal with NOA's special snowflake localizations if I don't have to.