Holy fuck you put a lot of thought into this. Great thread!
I myself would like the American Southwest/Rocky mountain range to be in a pokemon game (I'm a bit partial to that area because i live there). I think it would be different from what we've seen in other games.
The north part of the region could be giant peaks will small villages on them, and maybe a city could be inside a mountain. The south part could be a desert that has small cowboy towns scattered across the land and the main city of the region could be surrounded by an oasis.
Also the diverse wild life there could make some cool Pokemon. Some Pokemon could be a gila monster, a coyote, a true armadillo, a newt, a diamondback, a scorpion, and maybe a mountain lion if they haven't done one yet.
Predictions for global hardware sales by end of 2017: PS4 - 70M. Xbone - 33M. Switch - 7M.
"There is a need for parents to touch children first." - Tatsumi Kimishima, 2017