hershel_layton said: Just curious, but why do people feel as if their biological gender does not describe their actual "gender"? is there any science that can explain the mindset behind a transgender person?
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As with sexual orientation, sexual identity cannot be explained by hard science (see this for lots of thesis that went nowhere : https://en.wikipedia.org/wiki/Causes_of_transsexualism )
I guess you could look at psychology and sociology for an explanation about the mindset, mabe anthropology and looking into the societies that have a tradition of transvestism (lots of them, through theatre mostly).
History (yet another "soft" science) shows this mindset is not new : Georges Sand, born Amantine-Lucile-Aurore Dupin, famous french novelist and one of Chopin's lover, was described as "dressing up like a man, walking like a man and speaking like a man".