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They're not "OK", it's just that the government shouldn't be able to control what people do to themselves in their own home, and that criminalisation doesn't decrease drug use but it does increase organised crime and the numbers in prison.

You're also putting many types of drugs together when they vary considerably in effects and risks. Like LSD has very low risks if used advisably. And you're excluding alcohol and tobacco which have worse effects than many of the things that are 'drugs'.

Current drug policy and attitudes have no correlation with the actual effects of the drugs.