I understand your complaint about Platinum trophies. I hate that aswell especially when the online is dead in a game. But the MP for Uncharted 4 and TLOU were both pretty fun so I´ d be suprised if this one sucks. 

I really hope there isn´t co-op in it. I´m one of the few people who wasnt particularly fond of TLOU (But I can obviously see why it is one of the greatest PS games ever made although that honour will always be held by Ratchet and Clank a crack in time for me) I feel like it´d ruin the atmosphere a bit. Which I thought was one of the things TLOU completely nailed. 

 I’m more thinking along the lines of something similar to Uncharted 4’s Survival mode. I’m not interested in story co-op either, but a unique mode to compliment the multiplayer could be awesome. 

Hoping for...
-Infected Clickers actually being in it this time. Maybe creating situations where Enemy factions have to stop concentrating on each other and instead kill waves of infected. Would create a very interesting mix of gameplay. One second I have a gun pointed at your head but the next a wave of runners are coming and we both about face and watch each other's backs till they are gone.

-Social media interaction was super interesting in the first. Taking people's friend circle from facebook added an appealing level of incentive.

-Female combatants. This is pretty much assured. They are no longer shying away from the idea that women can be aggressors just like the men, as seen in the new trailers.

-Uncharted 4 level customization and flare.....but not it's shitty buying practice. NO MORE BLIND LOOT!!!

-Trophies: I don't know why they didn't do this with the first game because they did with Uncharted 2. MP based Trophies should be a DLC addition, IE not required for the game's platinum trophy. If they feel the NEED to put MP trophies in the Plat to push usage, than they should be marginal ones. Some people are adamant they are not in it for MP and I think it is shitty to force it on them.

As expected. Multiplayer is a nice treat but the campaign is the full course meal.